23. October 2018 | Indutech/Filtech

3M: for more purity and more efficient processes

Für mehr Reinheit und effizientere Prozesse
3M Emphaze AEX Hybrid Purifier is available in laboratory, pilot and production scales.

Source: 3M
3M Emphaze AEX Hybrid Purifier is a unique, all synthetic product platform designed for the purification of biopharmaceutical products. With its innovative filtration technology, it increases efficiency when filtering therapeutic proteins and other biopharmaceutical products. This helps to achieve high product purity early in the manufacturing process and a simplified, efficient downstream process.

The platform combines three 3M core technologies: advanced polymer materials, a novel anion exchange hydrogel nonwoven media and a fine particle, bioburden reduction multi-zone membrane. By combining the novel hydrogel nonwoven media with the multi-zone membrane, it achieves outstanding product purity in a single process step.

Outstanding purity with excellent product recovery
Even the smallest soluble and insoluble process impurities (< 0.1µm) are efficiently removed during cell culture clarification, resulting in superior turbidity reduction. This in turn provides protection of the valuable Protein A column resulting in even greater purity and efficiency in the downstream process. The result is an extremely low concentration of impurities with very high product yield. Even compared to high-quality depth filters, 3M Emphaze AEX Hybrid Purifier offers excellent throughput performance and can be easily incorporated into existing manufacturing processes. By providing protection to the chromatography column, the column’s performance is significantly enhanced. This makes the entire production process more effective and economical.
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